File Name: coronary artery disease signs and symptoms .zip
Are you a patient, family member, or caregiver? Heart disease differs significantly from other illnesses in its course and treatment. Hospice care for advanced cardiac disease addresses a wide range of symptoms, including shortness of breath, chest pain, weakness, functional decline and the management of fluid status.
There are three main types of coronary heart disease: obstructive coronary artery disease, nonobstructive coronary artery disease, and coronary microvascular disease. Coronary artery disease affects the large arteries on the surface of the heart. Many people have both obstructive and nonobstructive forms of this disease.
Coronary artery disease CAD , also called coronary heart disease CHD , ischemic heart disease IHD ,  or simply heart disease , involves the reduction of blood flow to the heart muscle due to build-up of plaque atherosclerosis in the arteries of the heart. Usually symptoms occur with exercise or emotional stress , last less than a few minutes, and improve with rest.
Risk factors include high blood pressure , smoking , diabetes , lack of exercise, obesity , high blood cholesterol , poor diet, depression , and excessive alcohol. Ways to reduce CAD risk include eating a healthy diet , regularly exercising, maintaining a healthy weight, and not smoking. In , CAD affected million people and resulted in 8. The narrowing of coronary arteries reduces the supply of oxygen-rich blood flowing to the heart, which becomes more pronounced during strenuous activities during which the heart beats faster.
The most common symptom is chest pain or discomfort that occurs regularly with activity, after eating, or at other predictable times; this phenomenon is termed stable angina and is associated with narrowing of the arteries of the heart. Angina also includes chest tightness, heaviness, pressure, numbness, fullness, or squeezing.
Unstable angina may precede myocardial infarction. Symptoms in women can differ from those in men, and the most common symptom reported by women of all races is shortness of breath. Women are less likely to recognize symptoms and seek treatment. Coronary artery disease has a number of well determined risk factors. These include high blood pressure , smoking , diabetes , lack of exercise, obesity , high blood cholesterol , poor diet, depression , family history , and excessive alcohol.
Dietary cholesterol does not appear to have a significant effect on blood cholesterol and thus recommendations about its consumption may not be needed. Limitation of blood flow to the heart causes ischemia cell starvation secondary to a lack of oxygen of the heart's muscle cells. The heart's muscle cells may die from lack of oxygen and this is called a myocardial infarction commonly referred to as a heart attack.
It leads to damage, death, and eventual scarring of the heart muscle without regrowth of heart muscle cells. Chronic high-grade narrowing of the coronary arteries can induce transient ischemia which leads to the induction of a ventricular arrhythmia , which may terminate into a dangerous heart rhythm known as ventricular fibrillation , which often leads to death.
Typically, coronary artery disease occurs when part of the smooth, elastic lining inside a coronary artery the arteries that supply blood to the heart muscle develops atherosclerosis.
With atherosclerosis, the artery's lining becomes hardened, stiffened, and accumulates deposits of calcium, fatty lipids, and abnormal inflammatory cells — to form a plaque.
Calcium phosphate hydroxyapatite deposits in the muscular layer of the blood vessels appear to play a significant role in stiffening the arteries and inducing the early phase of coronary arteriosclerosis.
This can be seen in a so-called metastatic mechanism of calciphylaxis as it occurs in chronic kidney disease and hemodialysis Rainer Liedtke Although these people suffer from a kidney dysfunction, almost fifty percent of them die due to coronary artery disease.
Plaques can be thought of as large "pimples" that protrude into the channel of an artery, causing a partial obstruction to blood flow. People with coronary artery disease might have just one or two plaques , or might have dozens distributed throughout their coronary arteries.
A more severe form is chronic total occlusion CTO when a coronary artery is completely obstructed for more than 3 months. Cardiac syndrome X is chest pain angina pectoris and chest discomfort in people who do not show signs of blockages in the larger coronary arteries of their hearts when an angiogram coronary angiogram is being performed.
Explanations include microvascular dysfunction or epicardial atherosclerosis. For symptomatic people, stress echocardiography can be used to make a diagnosis for obstructive coronary artery disease. The diagnosis of "Cardiac Syndrome X" — the rare coronary artery disease that is more common in women, as mentioned, is a diagnosis of exclusion. Therefore, usually, the same tests are used as in any person with the suspected of having coronary artery disease: [ citation needed ].
The diagnosis of coronary disease underlying particular symptoms depends largely on the nature of the symptoms. An X-ray of the chest and blood tests may be performed. In "stable" angina, chest pain with typical features occurring at predictable levels of exertion, various forms of cardiac stress tests may be used to induce both symptoms and detect changes by way of electrocardiography using an ECG , echocardiography using ultrasound of the heart or scintigraphy using uptake of radionuclide by the heart muscle.
If part of the heart seems to receive an insufficient blood supply, coronary angiography may be used to identify stenosis of the coronary arteries and suitability for angioplasty or bypass surgery. Diagnosis of acute coronary syndrome generally takes place in the emergency department , where ECGs may be performed sequentially to identify "evolving changes" indicating ongoing damage to the heart muscle.
Diagnosis is clear-cut if ECGs show elevation of the " ST segment ", which in the context of severe typical chest pain is strongly indicative of an acute myocardial infarction MI ; this is termed a STEMI ST-elevation MI and is treated as an emergency with either urgent coronary angiography and percutaneous coronary intervention angioplasty with or without stent insertion or with thrombolysis "clot buster" medication , whichever is available.
In the absence of ST-segment elevation, heart damage is detected by cardiac markers blood tests that identify heart muscle damage. If there is no evidence of damage, the term "unstable angina" is used. This process usually necessitates hospital admission and close observation on a coronary care unit for possible complications such as cardiac arrhythmias — irregularities in the heart rate.
Depending on the risk assessment, stress testing or angiography may be used to identify and treat coronary artery disease in patients who have had an NSTEMI or unstable angina. There are various risk assessment systems for determining the risk of coronary artery disease, with various emphasis on different variables above.
It is mainly based on age, gender, diabetes, total cholesterol, HDL cholesterol, tobacco smoking and systolic blood pressure. Polygenic score is another way of risk assessment. Medications and exercise are roughly equally effective. Most guidelines recommend combining these preventive strategies. A Cochrane Review found some evidence that counselling and education in an effort to bring about behavioral change might help in high-risk groups.
However, there was insufficient evidence to show an effect on mortality or actual cardiovascular events. In diabetes mellitus , there is little evidence that very tight blood sugar control improves cardiac risk although improved sugar control appears to decrease other problems such as kidney failure and blindness.
A diet high in fruits and vegetables decreases the risk of cardiovascular disease and death. The consumption of trans fat commonly found in hydrogenated products such as margarine has been shown to cause a precursor to atherosclerosis  and increase the risk of coronary artery disease. Evidence does not support a beneficial role for omega-3 fatty acid supplementation in preventing cardiovascular disease including myocardial infarction and sudden cardiac death.
Secondary prevention is preventing further sequelae of already established disease. Effective lifestyle changes include:. Aerobic exercise , like walking, jogging, or swimming, can reduce the risk of mortality from coronary artery disease. It also increases HDL cholesterol which is considered "good cholesterol". Although exercise is beneficial, it is unclear whether doctors should spend time counseling patients to exercise. The U. Preventive Services Task Force found "insufficient evidence" to recommend that doctors counsel patients on exercise but "it did not review the evidence for the effectiveness of physical activity to reduce chronic disease, morbidity and mortality", only the effectiveness of counseling itself.
Psychological symptoms are common in people with CHD, and while many psychological treatments may be offered following cardiac events, there is no evidence that they change mortality, the risk of revascularization procedures, or the rate of non-fatal myocardial infarction. There are a number of treatment options for coronary artery disease: .
In those with no previous history of heart disease, aspirin decreases the risk of a myocardial infarction but does not change the overall risk of death. Clopidogrel plus aspirin dual anti-platelet therapy reduces cardiovascular events more than aspirin alone in those with a STEMI. In others at high risk but not having an acute event, the evidence is weak.
Revascularization for acute coronary syndrome has a mortality benefit. As of , CAD was the leading cause of death globally resulting in over 7 million deaths. This may be secondary to a combination of genetic predisposition and environmental factors. Organizations such as the Indian Heart Association are working with the World Heart Federation to raise awareness about this issue. Coronary artery disease is the leading cause of death for both men and women and accounts for approximately , deaths in the United States every year.
Other terms sometimes used for this condition are "hardening of the arteries" and "narrowing of the arteries". The Infarct Combat Project ICP is an international nonprofit organization founded in which tries to decrease ischemic heart diseases through education and research.
In research into the archives of the [ failed verification ] Sugar Association , the trade association for the sugar industry in the US, had sponsored an influential literature review published in in the New England Journal of Medicine that downplayed early findings about the role of a diet heavy in sugar in the development of CAD and emphasized the role of fat; that review influenced decades of research funding and guidance on healthy eating.
Research efforts are focused on new angiogenic treatment modalities and various adult stem-cell therapies. A region on chromosome 17 was confined to families with multiple cases of myocardial infarction.
A more controversial link is that between Chlamydophila pneumoniae infection and atherosclerosis. Since the s the search for new treatment options for coronary artery disease patients, particularly for so called "no-option" coronary patients, focused on usage of angiogenesis  and adult stem cell therapies. Numerous clinical trials were performed, either applying protein angiogenic growth factor therapies, such as FGF-1 or VEGF , or cell therapies using different kinds of adult stem cell populations.
Research is still going on — with first promising results particularly for FGF-1   and utilization of endothelial progenitor cells. Myeloperoxidase has been proposed as a biomarker. Dietary changes can decrease coronary artery disease.
For example, data supports benefit from a plant-based diet and aggressive lipid lowering to improve heart disease. From Wikipedia, the free encyclopedia. Disease characterized by plaque building up in the arteries of the heart. Main article: Angina pectoris. Main article: Acute coronary syndrome. Main article: Diet and heart disease. Further information: Atheroma and Atherosclerosis. Southern Cross Healthcare Group. Archived from the original on 3 March Retrieved 15 September June Archived from the original on 12 September Archived from the original on 24 February Retrieved 23 February Archived from the original on 2 March Archived PDF from the original on 17 August Trends in Cardiovascular Medicine.
Retrieved 25 February Biomaterials for clinical applications Online-Ausg.
Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart called coronary arteries. Plaque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time. This process is called atherosclerosis. It is sometimes called coronary heart disease or ischemic heart disease.
Symptoms include chest pain or discomfort, shortness of breath, palpitations, faster heart rate, dizziness, nausea, extreme weakness and sweating.
Coronary artery disease CAD , also called coronary heart disease CHD , ischemic heart disease IHD ,  or simply heart disease , involves the reduction of blood flow to the heart muscle due to build-up of plaque atherosclerosis in the arteries of the heart. Usually symptoms occur with exercise or emotional stress , last less than a few minutes, and improve with rest. Risk factors include high blood pressure , smoking , diabetes , lack of exercise, obesity , high blood cholesterol , poor diet, depression , and excessive alcohol.
Coronary artery disease CAD is the most common type of heart disease. It is the leading cause of death in the United States in both men and women. CAD happens when the arteries that supply blood to heart muscle become hardened and narrowed.
The most common symptom of coronary artery disease is angina also called angina pectoris. Angina is often referred to as chest pain. It is also described as chest discomfort, heaviness, tightness, pressure, aching, burning, numbness, fullness, or squeezing.
Coronary artery disease CAD does not usually cause symptoms until it becomes advanced. Subtle symptoms can include dizziness, indigestion-like sensations, fatigue, and lack of energy.
Coronary artery disease develops when the major blood vessels that supply your heart become damaged or diseased. Cholesterol-containing deposits plaques in your coronary arteries and inflammation are usually to blame for coronary artery disease. The coronary arteries supply blood, oxygen and nutrients to your heart.
Coronary heart disease CHD , or coronary artery disease, develops when the coronary arteries become too narrow. The coronary arteries are the blood vessels that supply oxygen and blood to the heart. CHD tends to develop when cholesterol builds up on the artery walls, creating plaques.
Coronary artery disease CAD reduces the flow of blood to your heart. It happens when the arteries that supply blood to your heart muscle become narrowed and hardened due to fat and other substances accumulating into a plaque where the coronary artery is injured atherosclerosis. This can cause your heart to become weak and beat abnormally. Over time, it can lead to heart failure. Chest pain, shortness of breath, and other symptoms are associated with CAD. One common symptom of CAD is a type of chest pain called angina. Angina may feel like tightness, heaviness, or pressure in your chest.
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Хорошо, это ничего не дает.
Women are somewhat more likely than men are to have less typical signs and symptoms of a heart attack, such as neck or jaw pain. And they.Reply